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DUPUYTREN

What happens in Dupuytren's disease

Dupuytren's disease is a benign proliferation of the connective tissue of the hand. As it progresses, nodular thickenings and hardened cords form, at first in the palm and later at the thumb and the fingers. What increases are those connective-tissue fibres that connect the skin with the structures beneath it – tendon sheaths, ligaments, joint capsules and bone. The thickenings feel like (shortened) tendons. There is no actual shortening of the tendons, as is often mistakenly assumed.

Symptoms

As the fibrous cords shorten (not the tendons), the fingers bend more and more into the palm, and this cannot be overcome. At late stages the fingers can be fully folded into the hand.

Nodules in the palm

Painless hardenings can be felt in the hand

Nodules in the fingers

Painless hardenings can be felt in the hand

The fingers no longer straighten fully

The hand can no longer be laid flat on the table.

What causes the condition?

Dupuytren's disease is genetic. It is inherited in what is known as a multifactorial pattern, in which a generation can well be skipped. Whether diabetes mellitus or liver damage encourage the condition to develop is still disputed today.

Treatment options for Dupuytren's disease

As long as there are only hardenings in the hand, surgery should not yet be carried out. An operation on the hand only makes sense once the finger can no longer be straightened fully. Surgery cannot cure the condition completely. Even after a well-performed operation the nodules often cannot be prevented from returning. It is also unwise to wait too long, however, as the joints can otherwise stiffen

Treatment options

Non-surgical and surgical – we will find the right approach for you

Non-surgical

Radiotherapy

At an early stage the progress of the condition can be slowed by radiotherapy

Surgical

Removing the thickened tissue

Removing the thickened tissue improves the extension of the fingers.

Our hand specialists

Experienced consultants for Dupuytren's disease and hand surgery