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MATRIX-ASSOCIATED NANOFRACTURE

Method
Cartilage treatment for focal cartilage damage (knee, ankle)
Duration
30 to 45 minutes
Recovery time
3 to 6 months

How does matrix-associated nanofracture work?

Matrix-associated nanofracture is a modern procedure for treating well-defined cartilage defects in the knee or the ankle. The method combines classic microfracture with a biodegradable matrix that serves as a scaffold for regenerating tissue. The aim is to regenerate the damaged cartilage with a cartilage-like replacement structure – in a minimally invasive, gentle and effective way.

Cartilage damage in the knee or the ankle usually arises from injury or overuse and often leads to pain and restricted movement. In matrix-associated microdrilling the damaged cartilage is first smoothed arthroscopically. Targeted micro-holes are then drilled into the bone beneath, in order to stimulate the body's own regeneration through stem cells from the bone marrow.

An absorbable matrix (for instance collagen- or hyaluronate-based) is laid over the defect. This matrix offers the cells a stable structure in which to settle, differentiate and form new cartilage tissue. The operation is minimally invasive and can usually be carried out as a day case or with a short stay in hospital.

Rehabilitation after matrix-associated nanofracture

Healing after matrix-associated nanofracture proceeds in stages and is guided by the biological regeneration of the newly formed replacement cartilage. Targeted physiotherapy afterwards is decisive for the functional result.

Phase I (0-6 weeks): unloading and healing in

In the first phase it is decisive to protect the affected joint. Only partial weight-bearing is allowed, so as not to put the healing-in of the matrix at risk.

  • Crutches with partial weight-bearing (about 15-20 kg)
  • Cooling, elevation, lymphatic drainage
  • Passive mobilisation exercises (for instance a CPM splint)
Phase II (6-12 weeks): movement and building up muscle

Once healing-in is complete the load is increased step by step. The aim is to regain movement, co-ordination and muscle strength.

  • Progression to full weight-bearing
  • Active movement therapy, cycling
  • Isometric and later dynamic muscle training
Phase III (from 3 months): functional loading

The joint is now loaded increasingly as it would be in everyday life and in sport. The formation of cartilage-like replacement tissue is well advanced.

  • Balance training, co-ordination exercises
  • Building up muscle in open and closed chains
  • Sport-specific loading from about 6 months